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Mycology Research

Decoding the language of fungi — from mycorrhizal networks to bioactive compounds.

24
Active Projects
87
Publications
12
Research Partners
6
Patents Filed

Mycorrhizal Network Mapping

MycorrhizaeSoil EcologyAI

Our flagship project uses machine learning to map the vast underground mycorrhizal networks that connect forest ecosystems. By analyzing soil samples from 40 forest sites across North America, we are building the first comprehensive 3D model of how fungi, trees, and soil communicate.

Key Findings

Preliminary results show that mature forests maintain mycorrhizal networks spanning over 200 meters, with certain hub trees connecting to 47 or more neighboring trees. These networks facilitate nutrient transfer, drought resistance, and even chemical signaling between species.

Status

Active — Phase 2 data collection ongoing. Expected publication: Q3 2026 in Nature Ecology & Evolution.

Bioactive Compound Discovery

MedicinalPharmacologyBioprospecting

We screen rare and understudied fungal species for novel bioactive compounds. Our lab has identified 14 promising compounds with potential antibacterial, anti-inflammatory, and neuroprotective properties.

Recent Discovery

A compound isolated from Hericium coralloides (coral tooth fungus) shows remarkable neuroprotective activity in vitro, promoting nerve growth factor (NGF) production at rates 3x higher than currently known compounds. Patent filed, preclinical trials beginning 2026.

Status

Active — Compound isolation and characterization phase. Partnering with University of Washington Pharmacy School.

Mycelium-Based Materials

BioplasticsSustainabilityManufacturing

Exploring mycelium as a sustainable building material. Mycelium composites can replace plastics, insulation foams, and even leather. Our research focuses on optimizing growth parameters for structural integrity and commercial viability.

Achievements

Developed a mycelium composite with compressive strength exceeding 2.5 MPa — comparable to expanded polystyrene. Current formulations achieve full biodegradation in 45 days when composted.

Status

Scaling phase — Pilot manufacturing line being established. Targeting commercial packaging products by late 2026.

Fungal Bioremediation

EnvironmentalSoil RestorationEcotoxicology

Certain fungi can break down environmental pollutants — from oil spills to heavy metals to synthetic dyes. Our research identifies species with exceptional remediation capacity and develops deployment protocols for contaminated sites.

Field Studies

In collaboration with the EPA, we deployed Pleurotus ostreatus mycelium at three petroleum-contaminated sites. After 12 weeks, hydrocarbon levels dropped by 78-92%, significantly outperforming conventional bioremediation methods.

Status

Active — Expanding to heavy metal contamination sites in 2026. Seeking industrial partners for scaled deployment.

Recent Publications

Mycorrhizal Network Topology in Old-Growth Forests

Vasquez, E. et al. (2025). Nature Ecology & Evolution, 9(3), 234-251. DOI: 10.1038/s41559-025-02871-w

Neuroprotective Compounds from Hericium Species

Chen, M. et al. (2025). Journal of Ethnopharmacology, 327, 118-134. DOI: 10.1016/j.jep.2024.118134

Mycelium Composite Mechanical Properties Under Variable Growth Conditions

Okonkwo, S. et al. (2025). Biofabrication, 17(2), 025008. DOI: 10.1088/1758-5090/ad8a2b

Pleurotus ostreatus as a Bioremediation Agent for Petroleum-Contaminated Soils

Vasquez, E. & Chen, M. (2024). Environmental Science & Technology, 58(15), 6723-6735. DOI: 10.1021/acs.est.4c01234

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